Compact clear bottle with a white conical nasal nozzle and a transparent protective cap
Shown configuration · bottle with pump and cap / formulation, dip tube and label not shown

Nasal delivery

Nasal Spray Bottle

A bottle for a metered nasal pump on an 18-415 or 20-410 neck, delivering a fixed 0.05 to 0.1 mL per actuation within roughly a ten percent tolerance.

0.05–0.1 mL per actuation18-415 and 20-410 necksPreservative-free systems available
Stock status
In stock
Lead time
2–3 weeks
FOB price / pc
$0.95 - $1.40
MOQ
5,000 pcs

Final availability, dimensions, materials, assembled components and commercial terms are confirmed against the selected drawing and approved sample.

Dose is metered, not squeezed

The pump chamber fixes the volume

Priming is part of the dose

First actuations are not full doses

Nozzle shapes the plume

Angle and droplet size are formulation-linked

Nasal Spray Bottle profile

The bottle holds the formulation; the pump decides the dose and the plume.

Metering, priming & preservative strategy

Five things that determine what the patient actually receives.

A nasal spray delivers a fixed volume as a plume of droplets into a nasal cavity. The metering chamber in the pump sets the volume, the nozzle sets the spray geometry, and the bottle supplies the neck the pump clamps onto and the base the dip tube has to reach. All three have to be specified together.

01

Metering is a chamber, not a squeeze

Each actuation fills a small chamber and expels its contents, so the delivered volume is fixed at around 0.05 to 0.1 mL depending on the pump, typically held within about ten percent. That independence from how hard the patient presses is the whole reason a metered pump is specified rather than a squeeze bottle, which delivers whatever the hand decides.

02

Priming and re-priming are real losses

A new pump has air in the chamber and needs several actuations to deliver a full dose, and one left unused for days may need re-priming. Those actuations come out of the fill, so overfill is calculated to cover priming plus the labeled number of doses. A pack that ignores this runs out before the last labeled dose.

03

The nozzle sets the plume, and the plume matters clinically

Spray angle, droplet size distribution and plume geometry decide where in the nasal cavity the dose deposits. A finer plume carries further; a coarser one deposits anteriorly. These are measured properties of the pump and nozzle with a given formulation viscosity, which is why a formulation change can invalidate spray characterization even with identical hardware.

04

Preservative-free means a different pump architecture

A conventional pump draws air back into the bottle as it empties, which is why multi-dose nasal sprays are usually preserved. Preservative-free systems use a filter, a collapsing bag or a one-way valve to prevent that ingress. They cost more and change the bottle, and the decision is made with the formulation rather than added afterwards.

05

The dip tube has to reach a base it fits

The tube is cut to the internal height of that particular bottle, and a bottle with a punt or an uneven base leaves the last doses unreachable. On a small nasal pack that can be several labeled doses out of a month's supply, which is a patient-visible failure rather than a rounding error. Bottle and tube are dimensioned together.

06

Actuation force and stroke are part of the clinical evidence

The spray pattern that a nasal product is approved on is produced by a specific pump at a specific stroke, so a change in pump supplier or in actuator geometry is a change to the delivered product. That is why these components are locked in the specification and revalidated rather than substituted on price.

Application guide

A nasal pump has to fire upward, into a nostril.

Nasal packs are actuated inverted or near-vertical against soft tissue, which is a very different demand from a pump spraying downward onto skin. Priming and plume shape decide whether the dose reaches where it is aimed. These are development directions confirmed with the actual formulation.

Nasal Spray Bottle used for sprays used at home for congestion or allergy in a self-administration setting

Self-administration

Sprays used at home for congestion or allergy

For someone inserting a nozzle into one nostril, pressing while breathing in and repeating on the other side, often several times a day during a season. The nozzle taper has to sit comfortably without going too deep, and the actuation force has to suit a child or an older user.

  • Check nozzle taper against comfort
  • Confirm actuation force suits all users
  • Test the plume angle when near-vertical
Nasal Spray Bottle used for a spray picked up again after a quiet week in a seasonal use setting

Seasonal use

A spray picked up again after a quiet week

For allergy sprays a patient uses hard for a two weeks and then leaves in a drawer until the next flare-up. The metering chamber needs priming when new and again after days unused, and someone who presses once and feels nothing believes they have taken a dose they have not, so the count belongs in the instructions.

  • Count primes needed when new
  • Test restart after a week unused
  • State priming clearly in the instructions
Nasal Spray Bottle used for a tip that goes back into a coat in a carried in a pocket setting

Carried in a pocket

A tip that goes back into a coat

For sprays people keep on them and use twice a day, where the nozzle touches the inside of a nose and then goes back among keys and tissues. The cover is doing hygiene work rather than only stopping accidental actuation, and how the formula is preserved between doses is settled with the regulatory route.

  • Confirm the cover stays retained
  • Establish the preservation route
  • Follow nasal requirements by market

Applications describe development directions. Spray characteristics, nasal suitability, dose, sterility and regulatory outcomes are confirmed for the selected program.

Common questions

Nasal Spray Bottle questions

The pump is the product here. These questions are about how it behaves in a patient's hands.

How is the dose kept consistent?

A metering chamber. Each actuation fills a small fixed chamber and expels its contents, so delivered volume sits at around 0.05 to 0.1 mL depending on the pump, typically within about ten percent. Because it does not depend on how hard the patient presses, a metered pump behaves quite differently from a squeeze bottle delivering whatever the hand supplies.

Does the nozzle affect where the dose goes?

Yes. Spray angle, droplet size distribution and plume geometry determine whether the dose deposits anteriorly or carries further into the cavity. Those are measured properties of the pump and nozzle with a given formulation viscosity, which is why changing the formulation can invalidate spray characterization even when the hardware is unchanged.

Why do patients lose the last few doses?

Dip tube length against the base. The tube is cut to the internal height of that specific bottle, and a punt or an uneven base leaves the final doses unreachable. On a small nasal pack that can be several doses out of a month's supply, which patients notice and report. Bottle and tube are dimensioned together rather than sourced separately.

Is actuation force part of the clinical evidence?

It is. How hard the patient has to press and how far the actuator travels affect whether the dose is delivered as tested, so the force and stroke are recorded alongside the plume rather than treated as ergonomics. Changing the pump changes that evidence.

Next step

Send us the Nasal Spray Bottle brief.

Tell us the product, fill volume, closure preference and destination market. We will come back with the matching drawings, available configurations and a sample plan before anything is quoted.

  • 01Send the briefProduct, volume, closure and market
  • 02Get the optionsMatching drawings and configurations
  • 03Approve the sampleConfirm the pack before production